TAK1相关论文
目的 克隆细粒棘球绦虫（Eg）TAK1基因的开放阅读框（ORF）全长，预测其编码的蛋白EgTAK1的结构特点和生物学功能。方法 从新疆株细粒棘球蚴......
机体的天然免疫反应和炎症反应对于抵抗外来病原微生物的入侵十分重要。适当的天然免疫反应和炎症反应会对机体形成有效的保护,可......
背景:病理性心肌肥厚是心律失常和心力衰竭等多种不良心血管事件的独立危险因素,分子靶向治疗可以抑制心功能代偿期的心室肥厚,防......
醛脱氢酶1A1(ALDH1A1)是包括乳腺癌在内的多种癌症中肿瘤干细胞的功能性标志物,在肿瘤发生发展过程中扮演了重要角色.但是,ALDH1A1......
目的:利用病毒介导的基因操作技术及基因工程小鼠模型,研究中下部下丘脑（MBH）星形胶质细胞及小胶质细胞中的TAK1对小鼠焦虑样行为的......
目的血管平滑肌细胞（Vascular Smooth Muscle Cells,VSMCs）是血管壁的主要组成成分,它们的异常增殖和迁移是血管损伤后再狭窄、移植......
目的血管紧张素Ⅱ（AngⅡ）能够促进内源性心脏干细胞（cardiac stem cells,CSCs）向心肌样细胞分化。肿瘤坏死因子受体相关因子6（tumor nec......
研究背景:心血管疾病是一种严重威胁人类健康的疾病,其中高血压是心血管病的主要危险要素,持久性高血压可使动脉血管壁增厚或变硬,......
研究背景高血压作为心脑血管疾病发生的主要致病因素,同时也是导致肾脏发生损伤的重要原因。高血压肾病（Hypertensive Renal Diseas......
Molecular cloning and expression analysis of Epinephelus coioides TAK1 after Cryptocaryon irritans i
Cryptocaryon irritans a holotrichous ciliate is a marine fishe parasite,which can infect almost all kinds of marine fish......
Molecular cloning and expression analysis of Epinephelus coioides TAK1 after Cryptocaryon irritans i
Cryptocaryon irritans a holotrichous ciliate is a marine fishe parasite,which can infect almost all kinds of marine fish......
[目的]破骨细胞骨是人体内唯一具有骨吸收功能的细胞,在骨组织的动态平衡中起到关键作用。破骨细胞分化增多或其骨吸收活力的增强......
Raf kinase inhibitor protein mediates intestinal epithelial cell apoptosis and promotes inflammatory
Objective Raf kinase inhibitor protein (RKIP) appears to control cancer cell metastasis and its expression in colonic ti......
Cardiac hypertrophy is an adaptive response to the biomechanical stress,but it is the early event to induce cardiomyocyt......
目的 研究转化生长因子β激活激酶1 (TAK1)基因在三氯乙烯(TCE)所致小鼠接触性超敏反应(CHS)中的作用.方法 在ER-TAK1fl/fl小鼠双......
K63-linked TAK1 Polyubiquitination at Lys-158 Residue is Required for TNFα and IL-1 β-induced IKK/NF
TAK1 plays an easential role in proinflammatory cytokine TNFα and IL-1β-induced IKK/NF-κB and JNK/AP-1 activation.Her......
Cardiac hypertrophy is an adaptive response to the biomechanical stress,but it is the early event to induce cardiomyocyt......
目的 探讨胆红素对脾Toll样受体/核因子K B(TLR /NF-κ B)信号通路中磷酸化转化生长因子-B激活激酶1(TAK1,Transforming growth fa......
目的 研究上皮性卵巢癌中转化生长因子(transforming growth factor,TGF)-β1通过TAK1/β-catenin促进SK-OV-3细胞紫杉醇耐药的作......
Objective: To explore the mechanism of the action of Huoxue Huayu Lishui prescription on acute ankle joint injury. Metho......
Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer di
Chaperone-mediated autophagy (CMA) is a lysosome-dependent selective degradation pathway implicated in the pathogenesis ......
Catalpol counteracts the pathology in a mouse model of Duchenne muscular dystrophy by inhibiting the
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by a mutation in the gene encoding the d......
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CaMKⅡ promotes TLR-triggered proinflammatory cytokine and type Ⅰ interferon production by directly b
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会议
目的 观察硫辛酰胺(alpha-lipoamide,ALM)对糖尿病(diabetes Mellitus,DM)大鼠肾组织中转化生长因子β激活激酶1(TGFβ-activated-......
先天免疫对于硬骨鱼类抵抗病原微生物侵染而言至关重要。转化生长因子β激活激酶1(Transforming growth factor-β-activated kina......
研究目的:高血压心肌肥大由于压力负荷、血管紧张素II(Angiotensin II,AngⅡ)引起的疾病,它促进心血管发生的概率增加2-4倍,如不及......
IL-17是重要的促炎细胞因子之一,在多种炎性反应及自身免疫性疾病病理过程中具有重要作用。单核细胞趋化蛋白-1(monocyte chemoatt......
【目的】通过统计分析MAP4K4在食管鳞癌中的表达情况与临床病理特征以及预后情况之间联系,进一步用体外实验揭示MAP4K4表达改变对......
研究背景:Nedd8(Neural Precursor Cell Expressed Developmentally Downregulated 8)是一种类泛素蛋白,在 E1 活化酶(Nedd8-activ......
学位
目的:检测尖锐湿疣患者皮损组织和正常包皮组织中Livin、TAK1及JNK1的表达情况,探讨它们在尖锐湿疣发病及复发中的潜在生物学作用,......
背景:肝脏移植是治疗终末期肝脏疾病的唯一有效方法。缺血再灌注(I/R)损伤在肝脏移植过程中不可避免,是肝移植术后移植物功能障碍......
目的:1. 检测小鼠肝缺血再灌注（ischemia/reperfusion,I/R）损伤体外模型中Micro RNA-148a（miR-148a）、钙离子/钙调蛋白依赖蛋白激酶Ⅱ......
目的:观察转化生长因子β激活激酶1(TAK1)基因沉默对肿瘤坏死因子a(TNF-a)诱导的滑膜细胞中促炎介质白介素-6(IL-6)和白介素-8(IL-......
Objective Antimony (Sb) has recently been identified as a novel nerve poison, although the cellular and molecular mechan......
目的 探究环指蛋白(ring finger protein,RNF)4在心肌梗死(myocardial infarction,MI)后炎症反应中的作用及其机制.方法 心脏特异......
目的:探讨NF-κB信号传导通路中转化生长因子激活激酶1(TAK1)靶点对胃癌AGS细胞系增殖的影响。方法:利用si RNA沉默胃癌AGS细胞系......
,Compound FLZ inhibits lipopolysaccharide-induced inflammatory effects via down-regulation of the TA
Aim:The aim of this study was to investigate the effect of the squamosamide derivative FLZ (N-2-(4-hydroxy-phenyl)-ethyl......
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热休克蛋白90(Heat shock protein 90,Hsp90)是Hsp90家族成员,进化上高度保守,其结构主要由一个N端高度保守的ATPase结构域,一个中......
目的 利用RNA干扰技术研究沉默转化生长因子β激活激酶(TAK1)对三氧化二砷(As2O3)诱导的急性髓系白血病(AML)细胞增殖和凋亡的影响......
Molecular Characterization, Expression Profiles, and Immunostimulation Responses of TRAF6 and TAK1 i
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Expression and significance of transforming growth factor β-activated kinase 1 in uterine myoma tiss
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的:探讨转化生长因子β激活酶1(TAK1)在人食管癌组织中的表达及临床意义。方法:收集2002年9月至2008年2月在我院接受手术治疗的......
Objective Antimony(Sb)has recently been identified as a novel nerve poison,although the cellular and molecular mechanism......
